3-CHLOROBENZYLZINC CHLORIDE
3-Chlorobenzylzinc chloride
CAS: 312624-13-8
Molecular Formula: C7H6Cl2Zn
3-CHLOROBENZYLZINC CHLORIDE - Names and Identifiers
3-CHLOROBENZYLZINC CHLORIDE - Physico-chemical Properties
| Molecular Formula | C7H6Cl2Zn |
| Molar Mass | 226.42 |
| Density | 0.969g/mLat 25°C |
| Flash Point | -17°C |
| Storage Condition | 2-8°C |
3-CHLOROBENZYLZINC CHLORIDE - Risk and Safety
| Risk Codes | R19 - May form explosive peroxides R22 - Harmful if swallowed R36/38 - Irritating to eyes and skin. R40 - Limited evidence of a carcinogenic effect R36/37 - Irritating to eyes and respiratory system. R11 - Highly Flammable |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S33 - Take precautionary measures against static discharges. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 2056 3/PG 2 |
| WGK Germany | - |
3-CHLOROBENZYLZINC CHLORIDE - Introduction
3-Chlorobenzylzinc chloride is an organometallic compound with the chemical formula C7H5Cl2Zn. It has a white to yellow crystalline or powdery substance. The following is a detailed description of the nature, use, preparation and safety information of the 3-Chlorobenzylzinc chloride:
Nature:
1. Appearance: 3-Chlorobenzylzinc chloride is white to yellow crystal or powder substance.
2. Solubility: It is soluble in organic solvents such as ethanol and ether, but insoluble in water.
3. Melting Point: The melting point of 3-Chlorobenzylzinc chloride is about 205-210°C.
Use:
1. organic synthesis: 3-Chlorobenzylzinc chloride is an important reagent in organic synthesis, commonly used in alkylation, arylation, coupling and other reactions.
2. Catalyst: It can be used as a catalyst for reduction, coupling and cross-coupling reactions in organic synthesis reactions.
Preparation Method:
The preparation of 3-Chlorobenzylzinc chloride is generally obtained by reacting benzylated zinc with zinc chloride. Among them, benzylated zinc can be obtained by reacting phenyl lithium with a halogenated benzyl compound and then reacting with zinc chloride.
Safety Information:
1.3-Chlorobenzylzinc chloride is an organometallic compound that requires appropriate laboratory safety measures during operation.
2. It is irritating and may cause irritation to the skin, eyes and respiratory tract.
3. Avoid direct contact with skin and eyes when using, and make sure to operate in a well-ventilated place.
4. If contact occurs, rinse immediately with plenty of water and seek the help of a doctor.
5. in storage and handling should pay attention to fire and explosion-proof measures, away from fire and heat sources.
6. Mixtures with other compounds may produce dangerous chemical reactions, so mixing with other chemicals should be avoided.
Nature:
1. Appearance: 3-Chlorobenzylzinc chloride is white to yellow crystal or powder substance.
2. Solubility: It is soluble in organic solvents such as ethanol and ether, but insoluble in water.
3. Melting Point: The melting point of 3-Chlorobenzylzinc chloride is about 205-210°C.
Use:
1. organic synthesis: 3-Chlorobenzylzinc chloride is an important reagent in organic synthesis, commonly used in alkylation, arylation, coupling and other reactions.
2. Catalyst: It can be used as a catalyst for reduction, coupling and cross-coupling reactions in organic synthesis reactions.
Preparation Method:
The preparation of 3-Chlorobenzylzinc chloride is generally obtained by reacting benzylated zinc with zinc chloride. Among them, benzylated zinc can be obtained by reacting phenyl lithium with a halogenated benzyl compound and then reacting with zinc chloride.
Safety Information:
1.3-Chlorobenzylzinc chloride is an organometallic compound that requires appropriate laboratory safety measures during operation.
2. It is irritating and may cause irritation to the skin, eyes and respiratory tract.
3. Avoid direct contact with skin and eyes when using, and make sure to operate in a well-ventilated place.
4. If contact occurs, rinse immediately with plenty of water and seek the help of a doctor.
5. in storage and handling should pay attention to fire and explosion-proof measures, away from fire and heat sources.
6. Mixtures with other compounds may produce dangerous chemical reactions, so mixing with other chemicals should be avoided.
Last Update：2024-04-10 22:29:15
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QQ: 3007471201
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